|ESTP Thesis Award 2014 in Toxicological Pathology
The European Society of Toxicologic Pathology (ESTP) offers every second year an award for a thesis in toxicological pathology.
Winners in 2014:
- Dr. Alexandru-Flaviu Tabaran
honored with EUR 2,000 in recognition of his PhD thesis entitled "The Biodistribution, Toxicity and Application of Carbon Nanotubes in Cancer Therapy".
This thesis is an interesting contribution to the research on carbon nanotube based cancer therapy.
In his work Dr. Tabaran has investigated the tissue distribution and toxicity of carbon nanotubes after intraperitoneal injection in rats. Various methods were employed including Raman spectroscopy, electron and confocal microscopy, as well as light microscopy and immunohistochemistry. The application of carbon nanotubes in cancer therapy was investigated ex vivo in human pancreatic adenocarcinoma cells. This thesis is an important contribution to the field of nanomedicine and toxicology.
Alexandru-Flaviu Tabaran, The Biodistribution, Toxicity and Application of Carbon Nanotubes in Cancer Therapy 2012.
- Dr. Lieve Vangeel
honored with EUR 1,500 in recognition of her PhD thesis entitled "Bovine Sarcocystis species and their role in Bovine Eosinophilic Myositis".
This thesis is a valuable contribution to the research on the pathogenesis of Bovine Eosinophilic Myositis and diagnosis of Sarcocystis species.
In her work Dr. Vangeel has developed a molecular identification technique for bovine Sarcocystis species in both fresh and formalin-fixed material. Furthermore, she has investigated the prevalence of Sarcocystis in minced meat and in condemned carcasses. Finally, the pathogenesis of Bovine Eosinophilic Myositis was confirmed experimentally by inoculation of Sarcocystis antigen into calves. This work is also of interest to public health.
Lieve Vangeel, Bovine Sarcocystis species and their role in Bovine Eosinophilic Myositis 2012.
- Dr. Yanyong Sun
honored with EUR 1,000 in recognition of his PhD thesis entitled "Role of JAK-STAT signaling in the pathogenesis of astrogliosis in chronic demyelinating Theiler's murine encephalomyelitis".
This thesis is a valuable contribution to the research on the pathogenesis of Theiler's murine encephalomyelitis.
In his work Dr. Sun has investigated the mechanisms which lead to astrogliosis and remyelination failure. A combination of sophisticated methods including in vitro and in vivo studies, light microscopy, immunohistochemistry and microarray analysis was employed. A central role of the activated JAK-STAT pathway in the development of oligodendrocyte precursor cells towards astrocytic differentiation was found and suggested as a new target for treatment of demyelinating diseases.
Yanyong Sun, Role of JAK-STAT signaling in the pathogenesis of astrogliosis in chronic demyelinating Theiler's murine encephalomyelitis 2012
Berlin, August 29, 2014
|Dr. Frédéric Schorsch
Chairman of the ESTP
|Heike Marxfeld, PhD
Chair of the ESTP award committee