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| Digital slide: |
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| Species: |
Cynomolgus monkey |
| Strain/breeder: |
Philippines |
| Sex: |
Male |
| Age: |
4 years |
| Study type: |
108 days treatment |
| Treatment: |
Cyclosporine (Neoral®) 10 mg/kg p.o. + FTY 0.1 mg/kg p.o. + RAD 0.25 mg/kg p.o. |
| Animal status: |
108 days post-transplantation (kidney allograft) |
| Clinical findings: |
Serum creatinine: 107 µmol/L; serum urea 6.5 mmol/L |
| Organ(s): |
Kidney allograft |
Gross
finding(s): |
No abnormalities |
| Staining: |
H&E |
| Literature: |
| Schuurman HJ, Menninger K, Audet M, Kunkler A, Maurer C, Vedrine C, Bernhard M, Gaschen L, Brinkmann V, Quesniaux V.: Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combinationwith cyclosporine or RAD. Transplantation. 2002, 74: 951-960 |
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