ESTP/IFSTP Congress 2007: Case No 3


Digital slide(s):	Case 3a Case 3b
Species / breed:	Mouse, CB6F1/Jic-TgrasH2@Tac hemizygous
Sex:	Female
Age:	10 weeks (at start of dosing).
Study type:	26-week oral (dietary) carcinogenicity study in CB6F1-rasH2 mice
Treatment:	Positive control (MNU)
Clinical findings:	0410091_233F_25: Skin/fur, Ulcer (neck). Terminal sacrifice on test day 154; 0410091_244F_25: Mass (inguinal region left). Sacrificed for human reason test day 106
Organ(s):	Skin
Gross finding(s):	0410091_233F_25: Correlate to clinical observation; 0410091_244F_25: Single mass in the inguinal region left, approximately 3 cm long and 2 cm wide, nodular, cut surface: nodular. Correlate to clinical observation
Staining:	H&E