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GTP meeting 2001: Case No 5
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Species:
Rat
Strain/breeder:
Crl:Wist Han
Sex:
Male
Age:
15 Weeks
Study type:
26-Week oral toxicity study
Treatment:
VEGF-receptor tyrosine kinase inhibitor
Animal status:
Sacrifice before schedule after 7 weeks
Clinical findings:
White discoloration and fracture of teeth
Organ(s):
Teeth (incisors) and bone (femur/tibia)
Macroscopic
finding(s):
White discoloration and fracture of teeth
Staining:
H&E
Fig. 1 (128k)
Fig. 2 (130k)
Fig. 3 (94k)
Fig. 4 (126k)
Fig. 5 (118k)
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